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Home For the Community News & Publications Spotlight on Health Feature Story
Taking the first steps against human papillomavirus (HPV)

From Spotlight on Health Aug./Sept. 2007

Almost daily, Jon Dennis, M.D., gets
questions about the recently approved vaccine against cervical cancer.

“Parents are hearing a great deal about this in the media and want to learn more about it before making a decision for their daughters,” said Dennis, a pediatrician with CentraCare Clinic - Women & Children.

The Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine was approved
by the U.S. Food and Drug Administration (FDA) in June 2006 for females age 9 to 26.

The vaccine is designed to prevent 70 percent of cervical cancer and certain precancerous lesions, as well as 90 percent of genital warts. It is not intended to be used for treatment of these conditions and does not substitute for routine cervical cancer screening.

“Most importantly, it is the first vaccine approved to prevent a specific type of cancer,” Dennis said. “And the down side, I tell my patients, is that it’s a series of three shots.”

The review of vaccine reactions by the FDA primarily shows fainting and soreness. There has not been any pattern of unexpected severe side effects to date, Dennis said.

This three-injection vaccine is administered at two and six months after the first dose. The recommended age for vaccination of females is 11-12 years.

While the vaccine is still fairly new, Dennis said, the benefit of preventing this type of cancer far
outweighs the risks of side effects. But he also encourages anyone considering the vaccine to have this discussion with her personal physician.

“If I had a daughter that age, I would definitely encourage her to get the vaccine,” Dennis added.

Genital human papillomavirus (HPV) infects 6.2 million persons in the United States every year. During 2007, an estimated 11,100 new cases of cervical cancer will be diagnosed and approximately 3,700 women will die from this disease. In certain countries where Pap smear screening is not routine, cervical cancer is a common cancer in women.

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