Current Clinical Trials
All Cancers
A222004: A randomized phase III trial of olanzapine versus megestrol acetate for cancer associated anorexia.
Brain
NRG-BN001: A phase III trial of lomustine-temozolomide combination therapy versus standard temozolomide in patients with methylated MGMT promoter glioblastoma.
NRG-BN012: A randomized phase III trial of pre-operative compared to post-operative stereotactic radiosurgery in patients with respectable brain metastases.
Breast
NRG-BR007: A phase III clinical trial evaluating de-escalation of breast radiation for conservative treatment of stage I, hormone sensitive, HER2-Negative, oncotype recurrence score <18 breast cancer.
NRG-BR008: A phase III randomized trial of radiotherapy optimization for low-risk HER2-Positive breast cancer.
Genitourinary- Prostate
NRG-GU008: Randomized phase III trial incorporating abiraterone acetate with prednisone and apalutamide and advanced imaging into salvage treatment for patients with node-positive prostate cancer after radical prostatectomy.
Head & Neck
EA3132: RP2 radiotherapy with or without cisplatin for surgically resected squamous cell carcinoma of the head and neck (SCCHN) (pathological state III or IVA: T3-T4a, NO-3, M0 or T1-T2, N1-3, M0).
NRG-HN009: Randomized phase II/III trial of radiation with cisplatin at 100MG/M2 every three weeks versus radiation with weekly cisplatin at 40 MG/M2 for patients with locoregionally advanced squamous cell carcinoma of the head and neck (SCCHN).
RTOG-1216: Randomized phase II/III trial of adjuvant radiation therapy with cisplatin, docetaxel-cetuximab, or cisplatin-atezolizumab in pathological high-risk squamous cell cancer of the head.
Lung-NSCLC
NRG-LU008: Phase III prospective randomized trial of primary lung tumor stereotactic body radiation therapy followed by concurrent mediastinal chemoradiation for locally-advanced non-small cell lung cancer.
Lung-SCLC
NRG-CC009: Phase III trial of stereotactic radiosurgery (SCS) versus hippocampal-avoidant whole brain radiotherapy (HA-WBRT) for 10 or fewer brain metastases from small cell lung cancer.
NRG-LU007: Randomized phase II/III trial of consolidation radiation + immunotherapy for ES-SCLC: RAPTOR.
S1827: MRI brain surveillance alone versus MRI surveillance and prophylactic cranial irradiation (PCI): A randomized phase III trial in small-cell lung cancer (MAVERICK).
Patient must have an MRI of the brain performed within 28 days prior to registration documenting no evidence of brain metastases or leptomeningeal disease.
Research Network
CentraCare – Willmar Cancer Center is part of the Metro Minnesota Community Research Consortium, a non-profit research program sponsored by the National Cancer Institute (NCI). The NCI oversees clinical trials to help ensure you receive safe, high-quality care.
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